Active Ingredients (Per 3-Capsule Serving):
Vitamin C (as Ascorbic Acid USP) — Essential water-soluble antioxidant vitamin functioning as a critical enzymatic co-factor in the hydroxylation reactions required for serotonin neurotransmitter biosynthesis; supports adrenal cortex function, stress hormone metabolism, and neurological antioxidant protection against oxidative stress-related neurotransmitter depletion.
Niacin (as Niacinamide USP) — Bioavailable flush-free form of Vitamin B3 (Nicotinamide) serving as a direct co-enzyme precursor to NAD+ and NADP+ — the essential cellular energy molecules that fuel neurotransmitter synthesis enzymatic reactions; supports healthy nervous system function, neuronal energy metabolism, and GABA pathway activity.
Vitamin B6 (as Pyridoxal 5'-Phosphate — P-5-P) — The biologically active, pre-converted form of Vitamin B6 requiring no hepatic conversion; P-5-P is the essential enzymatic co-factor for the decarboxylase enzymes that convert L-DOPA to dopamine, 5-HTP to serotonin, and glutamate to GABA — making it arguably the single most critical neurotransmitter synthesis co-factor nutrient in the entire CERENITY formula.
Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid Glucosamine Salt — 5-MTHF) — The biologically active, already-methylated form of folate that bypasses the MTHFR genetic enzyme conversion pathway entirely; 5-MTHF is vital for supporting proper mood regulation, serving as a methyl group donor alongside Methylcobalamin B12 for neurotransmitter synthesis, and supporting healthy homocysteine metabolism — critical for adults with MTHFR gene variants who cannot efficiently convert standard folic acid.
Vitamin B12 (as Methylcobalamin) — The neurologically active, pre-methylated form of Vitamin B12 that crosses the blood-brain barrier more effectively than cyanocobalamin; Methylcobalamin works synergistically with Quatrefolic® 5-MTHF as a methyl group donor to maintain healthy neurotransmitter synthesis, support neurological myelin sheath integrity, and regulate homocysteine levels associated with neurological and cardiovascular health.
Magnesium (as DiMagnesium Malate) — Highly bioavailable, non-laxative magnesium chelate form combined with malic acid for superior gastrointestinal tolerability; calms the nervous system by directly binding to NMDA glutamate receptors to reduce excitatory neurotransmitter overactivity, works synergistically with Zinc Bisglycinate to reduce glutamate to non-toxic neuroprotective levels, and supports GABA receptor sensitivity and over 300 enzymatic reactions throughout the nervous system.
Zinc (as TRAACS® Zinc Bisglycinate Chelate) — The most bioavailable chelated zinc form available, certified by TRAACS® (The Real Amino Acid Chelate System); works synergistically with DiMagnesium Malate to reduce excitatory glutamate neurotransmitter levels to non-toxic ranges, providing significant neuroprotection; also supports GABA and serotonin synthesis pathway enzymatic activity and maintains healthy neurological immune function.
Inositol (NF grade) — A naturally occurring carbocyclic sugar alcohol and secondary messenger in the phosphatidylinositol signaling pathway that modulates serotonin, GABA, and dopamine receptor sensitivity in the brain; clinical applications include support for healthy stress response, OCD-spectrum thought patterns, and mood regulation — functioning as a critical intracellular neuromodulator amplifying the calming effects of serotonin and GABA neurotransmitter activity.
Taurine (USP grade) — A conditionally essential sulfonic amino acid found in the highest concentrations in the brain, heart, and retina; promotes inhibitory neurotransmission by directly activating GABA-A receptors in the thalamus (confirmed as a potent agonist in published neuroscience research), providing GABA-mimetic calming, neuroprotective, and anti-excitotoxic effects — significantly amplifying and extending the CNS relaxation activity of PharmaGABA™ in the CERENITY formula.
L-Theanine (as Suntheanine® — 100% pure L-isomer form from Camellia sinensis) — The world's most researched, patented L-Theanine ingredient backed by over 40 published human clinical studies; clinically demonstrated to significantly increase calming alpha brain wave activity, quickly improve stress perception and psychological resilience, modulate dopamine and serotonin receptor activity, reduce cortisol response to psychosocial stressors, and deliver a relaxed-but-alert cognitive state — without sedation or impairment of daytime mental performance.
Gamma-Aminobutyric Acid (as PharmaGABA™ — naturally fermented, non-synthetic) — The world's only naturally produced GABA supplement, biosynthesized through controlled fermentation by Lactobacillus hilgardii beneficial bacteria; clinically validated in published double-blind EEG research to produce a highly significant increase in alpha brain waves and significant decrease in stress-associated beta waves following 100 mg administration — confirming direct, measurable central nervous system relaxation activity that distinguishes PharmaGABA™ from synthetic GABA supplements.
5-HTP (5-Hydroxytryptophan from Griffonia simplicifolia seed extract) — The direct biosynthetic precursor to serotonin extracted from the seeds of the West African Griffonia simplicifolia plant; unlike L-Tryptophan, 5-HTP bypasses the rate-limiting tryptophan hydroxylase conversion step for faster, more efficient, and more consistent serotonin production — directly supporting healthy mood regulation, emotional stability, positive outlook, stress resilience, appetite regulation, and the serotonin-to-melatonin conversion pathway for sleep support.
Other Ingredients:
Natural Vegetable Capsules
Microcrystalline Cellulose
Magnesium Stearate
Silicon Dioxide
Free From: Wheat | Gluten | Soy | Animal Products | Dairy | Fish | Shellfish | Peanuts | Tree Nuts | Egg | Artificial Colors | Artificial Sweeteners | Artificial Preservatives | Non-GMO | Vegetarian Capsule | Practitioner-Exclusive Formula
