CERENITY PM

CERENITY PM

60 CT
$41.80
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CERENITY PM

CERENITY PM

$41.80

Supports restful sleep and nighttime recovery

Size

 CERENITY PM is a comprehensive practitioner-grade nighttime sleep and neurotransmitter support supplement specifically formulated for adults experiencing occasional sleeplessness, frequent nighttime waking, and stress-driven sleep cycle disruption. By delivering a synergistic blend of 5-HTP (150 mg), PharmaGABA® (150 mg), Taurine (300 mg), Phosphatidylserine (100 mg), DimaCal® Dicalcium Malate Calcium (250 mg), DiMagnesium Malate (150 mg), and essential neurotransmitter co-factor nutrients — CERENITY PM promotes a healthy circadian rhythm and sleep cycle by naturally boosting serotonin, GABA, and melatonin production, reducing HPA axis cortisol output overnight, calming excitatory glutamate neurotransmitter overactivity, and supporting deep, restorative, non-habit-forming sleep for adults with demanding, high-stress modern lifestyles.

KEY BENEFITS

Naturally Boosts Serotonin, GABA & Melatonin for a Complete Sleep Hormone Reset — CERENITY PM promotes a healthy sleep cycle by simultaneously supporting the body's own natural production of all three primary sleep-regulating neurochemicals — serotonin (via 5-HTP), gamma-aminobutyric acid (GABA via PharmaGABA® and Taurine), and melatonin (via the 5-HTP plus DimaCal® Calcium conversion pathway) — delivering a truly comprehensive nighttime neurotransmitter and sleep hormone restorative protocol unmatched by single-ingredient melatonin or GABA sleep supplements.

Clinically Proven to Reduce Sleep Latency by 20% & Increase Deep Sleep by 20% — CERENITY PM features PharmaGABA® — the world's only patented, naturally fermented, non-synthetic form of GABA produced by Lactobacillus hilgardii beneficial bacteria — clinically validated in a published bedtime administration study to reduce sleep latency (the time it takes to fall asleep) by 20% and simultaneously increase the time spent in deep, restorative slow-wave sleep stages by 20%, delivering measurable, clinically meaningful improvement in both sleep onset speed and sleep quality depth.

Lowers Nighttime Cortisol to Prevent Stress-Driven Sleep Disruption & Frequent Waking — CERENITY PM includes 100 mg of Phosphatidylserine (PS) — a phospholipid found in the highest concentrations in the brain — which has been clinically shown to regulate cortisol excretion from the hypothalamic-pituitary-adrenal (HPA) axis stress response system when taken in the evening; elevated nighttime cortisol is one of the primary biological drivers of frequent sleep disruption, nighttime waking, and non-restorative sleep in adults experiencing chronic daily stress.

Provides a Significant Natural Boost to Melatonin Levels Without Synthetic Melatonin — The unique combination of 5-HTP and DimaCal® Dicalcium Malate Calcium in CERENITY PM creates a powerful natural melatonin synthesis support system — 5-HTP directly increases serotonin production, which is then converted to melatonin, while Calcium ions serve as a critical enzymatic co-factor required in the final conversion step of serotonin to melatonin — delivering a meaningful, natural, dose-titratable melatonin boost without the dependency risk, next-day grogginess, or receptor desensitization associated with chronic synthetic melatonin supplementation.

Activates GABA Receptors via Multiple Synergistic Pathways for Maximum CNS Relaxation — CERENITY PM delivers multi-pathway nighttime GABA receptor activation through three complementary mechanisms: PharmaGABA® directly supplies naturally fermented GABA that promotes central nervous system (CNS) relaxation confirmed by published EEG brain wave research; Taurine (300 mg) acts as a potent direct agonist at extrasynaptic GABA-A receptors in the thalamus, significantly amplifying inhibitory neurotransmission; and DiMagnesium Malate calms the nervous system by reducing the activity of glutamate — the brain's primary excitatory neurotransmitter — at NMDA receptors.

Calms Excitatory Glutamate Overactivity for Stress-Free Mental Deactivation at Bedtime — DiMagnesium Malate in CERENITY PM promotes neurological relaxation by directly binding to and blocking NMDA glutamate receptors in the brain — the primary excitatory neurotransmitter signaling system that keeps the mind hyperactive, racing, and unable to wind down at bedtime in chronically stressed adults; the synergistic combination of DiMagnesium Malate and TRAACS® Zinc Bisglycinate Chelate together reduce glutamate to non-toxic neuroprotective levels, providing significant neuroprotection alongside their sleep-supporting calming effects.

Supports Healthy Circadian Rhythm Regulation & Sleep-Wake Cycle Optimization — CERENITY PM works in harmony with the body's internal biological clock — supporting the natural 24-hour circadian rhythm by providing the neurochemical building blocks (serotonin precursors, GABA, melatonin co-factors) the brain requires to execute its nightly metabolic and psychological reset process — making it an ideal long-term daily nighttime supplement for adults with disrupted circadian rhythms due to shift work, jet lag, blue light overexposure, high psychological stress, or age-related neurotransmitter decline.

Non-Habit-Forming, Non-Sedating Nighttime Sleep Support for Ongoing Daily Use — Unlike prescription sedatives, benzodiazepines, Z-drugs (zolpidem), or even high-dose synthetic melatonin supplements that carry dependency risk, receptor tolerance, and rebound insomnia concerns with chronic use — CERENITY PM supports sleep through natural neurotransmitter precursor replenishment and endogenous hormone synthesis activation, allowing the brain to produce and regulate its own sleep neurochemicals — making it a safe, sustainable, non-habit-forming nighttime sleep support supplement appropriate for consistent long-term use under practitioner supervision.

INGREDIENTS

Vitamin C (as Ascorbic Acid USP) — 50 mg — Essential water-soluble antioxidant vitamin co-factor required in the enzymatic hydroxylation steps of serotonin neurotransmitter biosynthesis; supports adrenal gland function, cortisol metabolism, and neurological antioxidant protection against overnight oxidative stress-related neurotransmitter depletion.

Niacin (as Niacinamide USP) — 10 mg — Bioavailable flush-free Vitamin B3 serving as a co-enzyme precursor to NAD+ — the essential cellular energy molecule fueling nighttime neurotransmitter synthesis enzymatic reactions; supports healthy nervous system function, neuronal energy metabolism, and GABA pathway enzymatic activity during the critical overnight sleep and neurological restoration phase.

Vitamin B6 (as Pyridoxal 5'-Phosphate — P-5-P) — 10 mg — The biologically active, pre-converted form of Vitamin B6 requiring no hepatic conversion; P-5-P is the indispensable enzymatic co-factor for the aromatic L-amino acid decarboxylase enzymes that convert 5-HTP directly into serotonin and glutamate into GABA — making it the single most critical nighttime neurotransmitter synthesis co-factor in the entire CERENITY PM formula.

Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid Glucosamine Salt — 5-MTHF) — 400 mcg — The biologically active, already-methylated form of folate that bypasses the MTHFR genetic enzyme conversion pathway entirely; vital for supporting healthy mood regulation through methyl group donation alongside Methylcobalamin for neurotransmitter synthesis; critical for adults with MTHFR gene variants unable to efficiently convert standard folic acid into the active form required for serotonin and GABA production.

Calcium (as DimaCal® Dicalcium Malate) — 250 mg — A uniquely bioavailable, stomach-friendly dicalcium malate chelate form providing two critical functions: Calcium ions serve as the essential enzymatic co-factor for the final N-acetyltransferase conversion step of serotonin to melatonin — making this ingredient a direct natural melatonin synthesis booster — while also contributing to muscle relaxation, nerve impulse regulation, and bone mineral density support overnight.

Magnesium (as DiMagnesium Malate) — 150 mg — Highly bioavailable, non-laxative magnesium malate chelate that calms the nervous system by binding to NMDA glutamate receptors and reducing excitatory neurotransmitter overactivity; promotes GABA receptor sensitivity; supports HPA axis stress response regulation; contributes to muscle relaxation, reduces nighttime leg cramps and restless sensations, and supports over 300 enzymatic reactions throughout the nervous system during overnight cellular restoration and neurological recovery.

Zinc (as TRAACS® Zinc Bisglycinate Chelate) — 5 mg — The most bioavailable chelated zinc form certified by TRAACS® (The Real Amino Acid Chelate System); works synergistically with DiMagnesium Malate to lower excitatory glutamate neurotransmitter levels to non-toxic neuroprotective concentrations; also supports GABA and serotonin synthesis pathway enzymatic activity and maintains healthy neurological immune function during sleep — the body's primary neurological immune restoration window.

Taurine (USP grade) — 300 mg — A conditionally essential sulfonic amino acid found in the highest concentrations in the brain and retina; confirmed in published neuroscience research as a potent direct agonist at extrasynaptic GABA-A receptors in the thalamus — delivering powerful GABA-mimetic inhibitory neurotransmission that significantly amplifies and extends the CNS relaxation, sleep-onset-supporting, and deep-sleep-promoting activity of PharmaGABA® in the CERENITY PM formula.

5-HTP (5-Hydroxytryptophan, from Griffonia simplicifolia seed extract) — 150 mg — The direct, immediately usable serotonin biosynthesis precursor extracted from West African Griffonia simplicifolia plant seeds; bypasses the rate-limiting tryptophan hydroxylase conversion step for faster, more reliable serotonin production than standard L-Tryptophan supplementation; elevated serotonin then provides the direct substrate for the pineal gland's nightly melatonin synthesis — delivering a dual serotonin-and-melatonin boost from a single ingredient for comprehensive nighttime neurotransmitter and sleep hormone support.

PharmaGABA® (Gamma-Aminobutyric Acid, naturally fermented via Lactobacillus hilgardii) — 150 mg — The world's only patented naturally produced GABA supplement — biosynthesized through controlled fermentation by Lactobacillus hilgardii beneficial bacteria; clinically validated in a published pre-bedtime administration study to reduce sleep latency by 20% and increase time in deep sleep by 20%; confirmed via published double-blind EEG study to produce a highly significant increase in calming alpha brain waves and significant decrease in stress-associated beta waves — establishing PharmaGABA® as the gold-standard natural GABA ingredient for nighttime sleep quality support.

Phosphatidylserine (from Soy Lecithin) — 100 mg — A naturally occurring phospholipid found in the highest concentrations in brain cell membranes; clinically shown to regulate cortisol excretion from the hypothalamic-pituitary-adrenal (HPA) axis stress response system when taken in the evening — directly targeting the elevated nighttime cortisol that drives frequent waking, non-restorative light sleep, and stress-driven sleep cycle disruption; also supports neuronal membrane integrity, cognitive function, and healthy memory consolidation during overnight sleep.

Other Ingredients:

Natural Vegetable Capsules
Microcrystalline Cellulose
Magnesium Stearate
Silicon Dioxide

Free From: Wheat | Gluten | Soy (Phosphatidylserine derived from soy lecithin — consult provider if soy-sensitive) | Animal Products | Dairy | Fish | Shellfish | Peanuts | Tree Nuts | Egg | Artificial Colors | Artificial Sweeteners | Artificial Preservatives | Non-GMO | Vegetarian Capsule | Practitioner-Exclusive Formula

HOW TO USE

Take all 4 capsules together 1–2 hours before your target bedtime — this timing allows 5-HTP to initiate the serotonin-to-melatonin conversion cascade, PharmaGABA® to begin its alpha brain wave and sleep latency reduction activity, and Phosphatidylserine to begin modulating HPA axis cortisol output before you attempt sleep

DISCLAIMER


This product is a dietary supplement intended to support general health and wellness. It is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult a qualified healthcare professional before use, especially if you are pregnant, nursing, taking medication, or have a medical condition.

Why Choose Us

Science-backed. Nature-inspired.

Every formula is crafted with clinical precision and sourced from nature's finest ingredients — because you deserve supplements that actually work.

Purity

Clean Ingredients

Zero fillers, no artificial additives. Every ingredient earns its place — third-party tested and transparently labelled.

100% transparent labelling
Efficacy

Clinically Dosed

Our formulas use research-backed doses — not proprietary blends — so you know exactly what you're getting and why.

Peer-reviewed formulations
Sourcing

Sustainably Sourced

From regenerative farms to GMP-certified facilities — our supply chain is built on integrity, traceability, and care.

GMP certified facilities
Results

Proven Results

Thousands of customers have transformed their health with our supplements. Real people. Real data. Real outcomes.

40,000+ satisfied customers
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Our supplements are formulated using clinically studied ingredients designed to support overall wellness, energy, and recovery. Each formula targets specific health needs while maintaining a clean and balanced composition. Results may vary depending on individual lifestyle and consistency.
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Our formulations are based on research-backed ingredients and established scientific studies. Products are manufactured in GMP-certified facilities to ensure quality, purity, and safety. We prioritize transparency and evidence-informed formulation standards.
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When used as directed, our supplements are generally safe for daily use as part of a balanced routine. We recommend consulting a healthcare professional before starting any new supplement, especially if you have existing conditions. Individual responses may vary.
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We focus on clean formulations and avoid unnecessary fillers, artificial colors, and harmful additives whenever possible. Each ingredient is selected for its purpose and quality. Our goal is to provide effective products without unnecessary extras.
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Results vary depending on the individual, product type, and consistency of use. Many customers begin noticing changes within 4 to 8 weeks of regular use. Maintaining a healthy lifestyle can help support optimal results.
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